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Karyopherin α-3 is a key protein in the pathogenesis of spinocerebellar ataxia type 3 controlling the nuclear localization of ataxin-3.
Sowa, Anna Sergeevna; Martin, Elodie; Martins, Inês Morgado; Schmidt, Jana; Depping, Reinhard; Weber, Jonasz Jeremiasz; Rother, Franziska; Hartmann, Enno; Bader, Michael; Riess, Olaf; Tricoire, Hervé; Schmidt, Thorsten.
Afiliación
  • Sowa AS; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, 72076 Tuebingen, Germany.
  • Martin E; Center for Rare Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
  • Martins IM; Graduate School of Cellular and Molecular Neuroscience, University of Tuebingen, 72074 Tuebingen, Germany.
  • Schmidt J; Degenerative Processes, Stress and Aging, CNRS UMR 8251, University Paris Diderot-Paris 7, 75205 Paris, France.
  • Depping R; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, 72076 Tuebingen, Germany.
  • Weber JJ; Center for Rare Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
  • Rother F; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, 72076 Tuebingen, Germany.
  • Hartmann E; Center for Rare Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
  • Bader M; Institute of Physiology, University of Luebeck, 23538 Luebeck, Germany.
  • Riess O; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, 72076 Tuebingen, Germany.
  • Tricoire H; Center for Rare Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
  • Schmidt T; Institute of Biology, University of Luebeck, 23538 Luebeck, Germany.
Proc Natl Acad Sci U S A ; 115(11): E2624-E2633, 2018 03 13.
Article en En | MEDLINE | ID: mdl-29476013
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Machado-Joseph / Transporte Activo de Núcleo Celular / Alfa Carioferinas / Ataxina-3 Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Alemania
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Machado-Joseph / Transporte Activo de Núcleo Celular / Alfa Carioferinas / Ataxina-3 Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Alemania