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BTKCys481Ser drives ibrutinib resistance via ERK1/2 and protects BTKwild-type MYD88-mutated cells by a paracrine mechanism.
Chen, Jiaji G; Liu, Xia; Munshi, Manit; Xu, Lian; Tsakmaklis, Nicholas; Demos, Maria G; Kofides, Amanda; Guerrera, Maria Luisa; Chan, Gloria G; Patterson, Christopher J; Meid, Kirsten; Gustine, Joshua; Dubeau, Toni; Severns, Patricia; Castillo, Jorge J; Hunter, Zachary R; Wang, Jinhua; Buhrlage, Sara J; Gray, Nathanael S; Treon, Steven P; Yang, Guang.
Afiliación
  • Chen JG; Bing Center for Waldenstrom's Macroglobulinemia.
  • Liu X; Bing Center for Waldenstrom's Macroglobulinemia.
  • Munshi M; Bing Center for Waldenstrom's Macroglobulinemia.
  • Xu L; Bing Center for Waldenstrom's Macroglobulinemia.
  • Tsakmaklis N; Bing Center for Waldenstrom's Macroglobulinemia.
  • Demos MG; Bing Center for Waldenstrom's Macroglobulinemia.
  • Kofides A; Bing Center for Waldenstrom's Macroglobulinemia.
  • Guerrera ML; Bing Center for Waldenstrom's Macroglobulinemia.
  • Chan GG; Bing Center for Waldenstrom's Macroglobulinemia.
  • Patterson CJ; Bing Center for Waldenstrom's Macroglobulinemia.
  • Meid K; Bing Center for Waldenstrom's Macroglobulinemia.
  • Gustine J; Bing Center for Waldenstrom's Macroglobulinemia.
  • Dubeau T; Bing Center for Waldenstrom's Macroglobulinemia.
  • Severns P; Bing Center for Waldenstrom's Macroglobulinemia.
  • Castillo JJ; Bing Center for Waldenstrom's Macroglobulinemia.
  • Hunter ZR; Department of Medical Oncology, Dana Farber Cancer Institute, and.
  • Wang J; Bing Center for Waldenstrom's Macroglobulinemia.
  • Buhrlage SJ; Department of Medical Oncology, Dana Farber Cancer Institute, and.
  • Gray NS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Treon SP; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Yang G; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
Blood ; 131(18): 2047-2059, 2018 05 03.
Article en En | MEDLINE | ID: mdl-29496671
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Resistencia a Antineoplásicos / Comunicación Paracrina / Sistema de Señalización de MAP Quinasas / Factor 88 de Diferenciación Mieloide / Agammaglobulinemia Tirosina Quinasa / Mutación Límite: Humans Idioma: En Revista: Blood Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Resistencia a Antineoplásicos / Comunicación Paracrina / Sistema de Señalización de MAP Quinasas / Factor 88 de Diferenciación Mieloide / Agammaglobulinemia Tirosina Quinasa / Mutación Límite: Humans Idioma: En Revista: Blood Año: 2018 Tipo del documento: Article