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2-Aminopyridine-Based Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Inhibitors: Assessment of Mechanism-Based Safety.
Dow, Robert L; Ammirati, Mark; Bagley, Scott W; Bhattacharya, Samit K; Buckbinder, Leonard; Cortes, Christian; El-Kattan, Ayman F; Ford, Kristen; Freeman, Gary B; Guimarães, Cristiano R W; Liu, Shenping; Niosi, Mark; Skoura, Athanasia; Tess, David.
Afiliación
  • Dow RL; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Ammirati M; Pfizer Worldwide Research & Development , Groton , Connecticut 06340 , United States.
  • Bagley SW; Pfizer Worldwide Research & Development , Groton , Connecticut 06340 , United States.
  • Bhattacharya SK; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Buckbinder L; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Cortes C; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • El-Kattan AF; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Ford K; Pfizer Worldwide Research & Development , Groton , Connecticut 06340 , United States.
  • Freeman GB; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Guimarães CRW; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Liu S; Pfizer Worldwide Research & Development , Groton , Connecticut 06340 , United States.
  • Niosi M; Pfizer Worldwide Research & Development , Groton , Connecticut 06340 , United States.
  • Skoura A; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
  • Tess D; Pfizer Worldwide Research & Development , Cambridge , Massachusetts 02139 , United States.
J Med Chem ; 61(7): 3114-3125, 2018 04 12.
Article en En | MEDLINE | ID: mdl-29570292
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Serina-Treonina Quinasas / Péptidos y Proteínas de Señalización Intracelular / Inhibidores de Proteínas Quinasas / Aminopiridinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Serina-Treonina Quinasas / Péptidos y Proteínas de Señalización Intracelular / Inhibidores de Proteínas Quinasas / Aminopiridinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos