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Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Zyryanova, Alisa F; Weis, Félix; Faille, Alexandre; Alard, Akeel Abo; Crespillo-Casado, Ana; Sekine, Yusuke; Harding, Heather P; Allen, Felicity; Parts, Leopold; Fromont, Christophe; Fischer, Peter M; Warren, Alan J; Ron, David.
Afiliación
  • Zyryanova AF; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK. az310@cam.ac.uk ajw1000@cam.ac.uk dr360@medschl.cam.ac.uk.
  • Weis F; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
  • Faille A; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Alard AA; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Crespillo-Casado A; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
  • Sekine Y; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
  • Harding HP; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Allen F; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Parts L; Division of Biomolecular Science and Medicinal Chemistry, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK.
  • Fromont C; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
  • Fischer PM; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
  • Warren AJ; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
  • Ron D; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
Science ; 359(6383): 1533-1536, 2018 03 30.
Article en En | MEDLINE | ID: mdl-29599245
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factor 2B Eucariótico de Iniciación / Ciclohexilaminas / Acetamidas Límite: Animals / Humans Idioma: En Revista: Science Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factor 2B Eucariótico de Iniciación / Ciclohexilaminas / Acetamidas Límite: Animals / Humans Idioma: En Revista: Science Año: 2018 Tipo del documento: Article