Role of association of OmpK35 and OmpK36 alteration and bla<sub>ESBL</sub> and/or bla<sub>AmpC</sub> genes in conferring carbapenem resistance among non-carbapenemase-producing Klebsiella pneumoniae.

Hamzaoui, Zaineb; Ocampo-Sosa, Alain; Fernandez Martinez, Marta; Landolsi, Sarrah; Ferjani, Sana; Maamar, Elaa; Saidani, Mabrouka; Slim, Amine; Martinez-Martinez, Luis; Boutiba-Ben Boubaker, Ilhem

Role of association of OmpK35 and OmpK36 alteration and bla_ESBL and/or bla_AmpC genes in conferring carbapenem resistance among non-carbapenemase-producing Klebsiella pneumoniae.

Hamzaoui, Zaineb; Ocampo-Sosa, Alain; Fernandez Martinez, Marta; Landolsi, Sarrah; Ferjani, Sana; Maamar, Elaa; Saidani, Mabrouka; Slim, Amine; Martinez-Martinez, Luis; Boutiba-Ben Boubaker, Ilhem.

Afiliación

Hamzaoui Z; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia; University of Carthage, Faculty of Sciences of Bizerte, Tunis, Tunisia. Electronic address: zaineb.hamzaoui@hotmail.com.
Ocampo-Sosa A; Service of Microbiology, University Hospital Marqués de Valdecilla-IDIVAL, Santander 39008, Spain.
Fernandez Martinez M; Service of Microbiology, University Hospital Marqués de Valdecilla-IDIVAL, Santander 39008, Spain.
Landolsi S; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia.
Ferjani S; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia; University of Carthage, Faculty of Sciences of Bizerte, Tunis, Tunisia.
Maamar E; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia.
Saidani M; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia; Charles Nicolle Hospital, Laboratory of Microbiology, 1006 Tunis, Tunisia.
Slim A; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia; Charles Nicolle Hospital, Laboratory of Microbiology, 1006 Tunis, Tunisia.
Martinez-Martinez L; Clinical Unit of Microbiology, University Hospital Reina Sofía, Córdoba, Spain; Department of Microbiology, University of Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain.
Boutiba-Ben Boubaker I; University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09 Research Laboratory 'Antimicrobial resistance', 1007 Tunis, Tunisia; Charles Nicolle Hospital, Laboratory of Microbiology, 1006 Tunis, Tunisia.

Int J Antimicrob Agents ; 52(6): 898-905, 2018 Dec.

Article en En | MEDLINE | ID: mdl-29621592

Asunto(s)

Antibacterianos/farmacología; Proteínas Bacterianas/genética; Carbapenémicos/farmacología; Farmacorresistencia Bacteriana Múltiple; Klebsiella pneumoniae/efectos de los fármacos; Porinas/genética; beta-Lactamasas/genética; Proteínas Bacterianas/análisis; Electroforesis en Gel de Poliacrilamida; Humanos; Klebsiella pneumoniae/genética; Pruebas de Sensibilidad Microbiana; Tipificación Molecular; Mutación; Porinas/deficiencia; Análisis de Secuencia de ADN; Túnez; beta-Lactamasas/análisis; beta-Lactamasas/metabolismo

Palabras clave

Carbapenem; Klebsiella pneumoniae; Outer membrane porin; Resistance

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Beta-Lactamasas / Carbapenémicos / Porinas / Farmacorresistencia Bacteriana Múltiple / Klebsiella pneumoniae / Antibacterianos Tipo de estudio: Risk_factors_studies Límite: Humans País/Región como asunto: Africa Idioma: En Revista: Int J Antimicrob Agents Año: 2018 Tipo del documento: Article

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