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Reversible, orally available ADP receptor (P2Y12) antagonists Part I: Hit to lead process.
Islam, Imadul; Yuan, Shendong; Wei, Robert G; Xu, Wei; Morrissey, Michael; Mohan, Raju; Zheng, Dewan; DiMella, Andrea; Dunning, Laura; Snider, Michael; Subramanyam, Babu; Tseng, Jih-Lie; Bryant, Judi A; Buckman, Brad O.
Afiliación
  • Islam I; Medical Core Facility and Research Platforms, King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh 11426, Saudi Arabia; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive,
  • Yuan S; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Wei RG; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Xu W; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Morrissey M; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Mohan R; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Zheng D; Department of Molecular Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • DiMella A; Department of Molecular Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Dunning L; Department of Molecular Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Snider M; Department of Molecular Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Subramanyam B; Department of Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Tseng JL; Department of Pharmacology, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Bryant JA; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
  • Buckman BO; Department of Medicinal Chemistry, Berlex Biosciences, 2600 Hilltop Drive, Richmond, CA 94804, United States.
Bioorg Med Chem Lett ; 28(9): 1459-1463, 2018 05 15.
Article en En | MEDLINE | ID: mdl-29628327
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores Purinérgicos P2Y12 / Fluorenos Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores Purinérgicos P2Y12 / Fluorenos Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article