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FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Qamar, Seema; Wang, GuoZhen; Randle, Suzanne J; Ruggeri, Francesco Simone; Varela, Juan A; Lin, Julie Qiaojin; Phillips, Emma C; Miyashita, Akinori; Williams, Declan; Ströhl, Florian; Meadows, William; Ferry, Rodylyn; Dardov, Victoria J; Tartaglia, Gian G; Farrer, Lindsay A; Kaminski Schierle, Gabriele S; Kaminski, Clemens F; Holt, Christine E; Fraser, Paul E; Schmitt-Ulms, Gerold; Klenerman, David; Knowles, Tuomas; Vendruscolo, Michele; St George-Hyslop, Peter.
Afiliación
  • Qamar S; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.
  • Wang G; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.
  • Randle SJ; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.
  • Ruggeri FS; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Varela JA; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Lin JQ; Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.
  • Phillips EC; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.
  • Miyashita A; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 3H2, Canada.
  • Williams D; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 3H2, Canada.
  • Ströhl F; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Meadows W; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK.
  • Ferry R; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 3H2, Canada.
  • Dardov VJ; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Tartaglia GG; Centre for Genomic Regulation, the Barcelona Institute for Science and Technology, 08003 Barcelona, Spain; Universitat Pompeu Fabra, 08003 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Spain.
  • Farrer LA; Departments of Medicine, Neurology, and Ophthalmology and Departments of Epidemiology and Biostatistics, Boston University, Boston, MA 02118, USA.
  • Kaminski Schierle GS; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Kaminski CF; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Holt CE; Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK.
  • Fraser PE; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 3H2, Canada.
  • Schmitt-Ulms G; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 3H2, Canada.
  • Klenerman D; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Knowles T; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK.
  • Vendruscolo M; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • St George-Hyslop P; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0XY, UK; Tanz Centre for Research in Neurodegenerative Diseases and Departments of Medicine, Medical Biophysics and Laboratory Medicine and Pathobiology, University of Toronto, Toro
Cell ; 173(3): 720-734.e15, 2018 04 19.
Article en En | MEDLINE | ID: mdl-29677515
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arginina / Chaperonas Moleculares / Proteína FUS de Unión a ARN Límite: Animals / Humans Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arginina / Chaperonas Moleculares / Proteína FUS de Unión a ARN Límite: Animals / Humans Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido