Displaying 31RG-1 peptide on the surface of HPV16 L1 by use of a human papillomavirus chimeric virus-like particle induces cross-neutralizing antibody responses in mice.

Chen, Xue; Zhang, Ting; Liu, Hongyang; Hao, Yaru; Liao, Guoyang; Xu, Xuemei

Chen, Xue; Zhang, Ting; Liu, Hongyang; Hao, Yaru; Liao, Guoyang; Xu, Xuemei.

Afiliación

Chen X; a Department of Biophysics and Structural Biology , Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College , Beijing , China.
Zhang T; a Department of Biophysics and Structural Biology , Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College , Beijing , China.
Liu H; a Department of Biophysics and Structural Biology , Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College , Beijing , China.
Hao Y; a Department of Biophysics and Structural Biology , Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College , Beijing , China.
Liao G; b The Fifth Department of Biological Products , Institute of Medical Biology, Chinese Academy of Medical Science, Peking Union Medical College , Yunnan , China.
Xu X; a Department of Biophysics and Structural Biology , Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College , Beijing , China.

Hum Vaccin Immunother ; 14(8): 2025-2033, 2018.

Article en En | MEDLINE | ID: mdl-29683766

Asunto(s)

Papillomavirus Humano 16/inmunología; Papillomavirus Humano 31/inmunología; Infecciones por Papillomavirus/prevención & control; Vacunas contra Papillomavirus/inmunología; Vacunas de Partículas Similares a Virus/inmunología; Animales; Anticuerpos Antivirales/sangre; Anticuerpos Antivirales/inmunología; Proteínas de la Cápside/genética; Proteínas de la Cápside/inmunología; Protección Cruzada/genética; Protección Cruzada/inmunología; Evaluación Preclínica de Medicamentos; Femenino; Papillomavirus Humano 16/genética; Papillomavirus Humano 31/genética; Ratones; Ratones Endogámicos BALB C; Modelos Animales; Proteínas Oncogénicas Virales/genética; Proteínas Oncogénicas Virales/inmunología; Infecciones por Papillomavirus/inmunología; Infecciones por Papillomavirus/virología; Vacunas contra Papillomavirus/genética; Péptidos; Ingeniería de Proteínas; Vacunas de Partículas Similares a Virus/genética

Palabras clave

HPV31 L2 peptide; broad-spectrum vaccine; chimeric virus-like particles; cross-neutralizing antibody; human papillomavirus

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Infecciones por Papillomavirus / Papillomavirus Humano 16 / Vacunas contra Papillomavirus / Papillomavirus Humano 31 / Vacunas de Partículas Similares a Virus Límite: Animals Idioma: En Revista: Hum Vaccin Immunother Año: 2018 Tipo del documento: Article País de afiliación: China

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