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The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression.
Ali, Mina; Ajore, Ram; Wihlborg, Anna-Karin; Niroula, Abhishek; Swaminathan, Bhairavi; Johnsson, Ellinor; Stephens, Owen W; Morgan, Gareth; Meissner, Tobias; Turesson, Ingemar; Goldschmidt, Hartmut; Mellqvist, Ulf-Henrik; Gullberg, Urban; Hansson, Markus; Hemminki, Kari; Nahi, Hareth; Waage, Anders; Weinhold, Niels; Nilsson, Björn.
Afiliación
  • Ali M; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Ajore R; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Wihlborg AK; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Niroula A; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Swaminathan B; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Johnsson E; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Stephens OW; Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Morgan G; Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Meissner T; Department of Molecular and Experimental Medicine, Avera Cancer Institute, Sioux Falls, SD, 57105, USA.
  • Turesson I; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Goldschmidt H; Department of Internal Medicine V, University of Heidelberg, 69117, Heidelberg, Germany.
  • Mellqvist UH; National Center for Tumor Diseases, Ulm, 69120, Heidelberg, Germany.
  • Gullberg U; Section of Hematology, South Elvsborg Hospital, SE 501 83, Borås, Sweden.
  • Hansson M; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Hemminki K; Department of Laboratory Medicine, Hematology and Transfusion Medicine, SE 221 84, Lund, Sweden.
  • Nahi H; Hematology Clinic, Skåne University Hospital, SE 221 85, Lund, Sweden.
  • Waage A; German Cancer Research Center, 69120, Heidelberg, Germany.
  • Weinhold N; Center for Primary Health Care Research, Lund University, SE 205 02, Malmö, Sweden.
  • Nilsson B; Center for Hematology and Regenerative Medicine, Karolinska Institutet, SE 171 77, Stockholm, Sweden.
Nat Commun ; 9(1): 1649, 2018 04 25.
Article en En | MEDLINE | ID: mdl-29695719
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Ribosómicas / Cromosomas Humanos Par 5 / Regulación Neoplásica de la Expresión Génica / Factores de Elongación Transcripcional / Alelos / Mieloma Múltiple Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Suecia
Texto completo
Imprimir
XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Ribosómicas / Cromosomas Humanos Par 5 / Regulación Neoplásica de la Expresión Génica / Factores de Elongación Transcripcional / Alelos / Mieloma Múltiple Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2018 Tipo del documento: Article País de afiliación: Suecia