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Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic ß-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection.
Zhu, Xiao-Xue; Zhu, Da-Long; Li, Xiao-Ying; Li, Ya-Lin; Jin, Xiao-Wei; Hu, Tian-Xin; Zhao, Yu; Li, Yong-Guo; Zhao, Gui-Yu; Ren, Shuang; Zhang, Yi; Ding, Yan-Hua; Chen, Li.
Afiliación
  • Zhu XX; Phase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.
  • Zhu DL; Department of Endocrinology and Metabolism, Nanjing Drum Hospital, Nanjing University Medical School, Nanjing, China.
  • Li XY; Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Li YL; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Jin XW; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Hu TX; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Zhao Y; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Li YG; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Zhao GY; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Ren S; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Zhang Y; Hua Medicine (Shanghai) Limited, Shanghai, China.
  • Ding YH; Phase I Clinical Trial Unit, The First Hospital of Jilin University, Changchun, China.
  • Chen L; Hua Medicine (Shanghai) Limited, Shanghai, China.
Diabetes Obes Metab ; 20(9): 2113-2120, 2018 09.
Article en En | MEDLINE | ID: mdl-29707866
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Selección de Paciente / Activadores de Enzimas / Diabetes Mellitus Tipo 2 / Glucoquinasa / Hipoglucemiantes Tipo de estudio: Clinical_trials Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2018 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Selección de Paciente / Activadores de Enzimas / Diabetes Mellitus Tipo 2 / Glucoquinasa / Hipoglucemiantes Tipo de estudio: Clinical_trials Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2018 Tipo del documento: Article País de afiliación: China