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Desmoplastic melanoma of the oral cavity: diagnostic pitfalls and clinical characteristics.
Min, Seung-Ki; Jeong, Joo Hee; Ahn, Kang-Min; Yoo, Chong Woo; Park, Joo Yong; Choi, Sung Weon.
Afiliación
  • Min SK; Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • Jeong JH; Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • Ahn KM; Department of Oral and Maxillofacial Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Yoo CW; Department of Pathology, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • Park JY; Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • Choi SW; Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
J Korean Assoc Oral Maxillofac Surg ; 44(2): 66-72, 2018 Apr.
Article en En | MEDLINE | ID: mdl-29732311
OBJECTIVES: Desmoplastic melanoma of the oral cavity is an extremely rare condition that is often confused on initial diagnosis with non-melanotic benign lesion or spindle cell tumors. The purpose of this article was to raise awareness of the disease using a literature review. MATERIALS AND METHODS: We analyzed 19 desmoplastic melanoma cases reported in the literature and added our experience. Data on clinical, histopathology, treatment, and survival were retrieved and analyzed. Survival analysis was by the Kaplan-Meier method. RESULTS: Initial clinical and histopathological features were indistinctive, and a definite diagnosis of desmoplastic melanoma at initial assessment was possible in only 23.5% of cases. Among tests, immunohistochemical studies for S-100 and vimentin were all positive. The 5-year disease-free survival rate for oral desmoplastic melanoma was 0%, and the 5-year overall survival rate was 55.0%. CONCLUSION: Oral desmoplastic melanoma has a high percentage of initial misdiagnosis and propensity for local recurrence. Thus, careful initial diagnosis and adequate surgery may result in improved overall survival.
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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Korean Assoc Oral Maxillofac Surg Año: 2018 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Korean Assoc Oral Maxillofac Surg Año: 2018 Tipo del documento: Article