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Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.
Wu, Shuai; He, Yunjiao; Qiu, Xianxiu; Yang, Wenchao; Liu, Wenchao; Li, Xiaohua; Li, Yan; Shen, Han-Ming; Wang, Renxiao; Yue, Zhenyu; Zhao, Yanxiang.
Afiliación
  • Wu S; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
  • He Y; The Hong Kong Polytechnic University Shenzhen Research Institute, 518057 Shenzhen, People's Republic of China.
  • Qiu X; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
  • Yang W; Department of Biology, Southern University of Science and Technology, 518055 Shenzhen, People's Republic of China.
  • Liu W; Shenzhen Key Laboratory of Cell Microenvironment, Southern University of Science and Technology, 518055 Shenzhen, People's Republic of China.
  • Li X; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
  • Li Y; The Hong Kong Polytechnic University Shenzhen Research Institute, 518057 Shenzhen, People's Republic of China.
  • Shen HM; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
  • Wang R; The Hong Kong Polytechnic University Shenzhen Research Institute, 518057 Shenzhen, People's Republic of China.
  • Yue Z; Key Laboratory of Pesticide and Chemical Biology of the Ministry of Education, College of Chemistry, Central China Normal University, 430079 Wuhan, People's Republic of China.
  • Zhao Y; Department of Applied Biology and Chemical Technology, State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
Proc Natl Acad Sci U S A ; 115(25): E5669-E5678, 2018 06 19.
Article en En | MEDLINE | ID: mdl-29866835

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos / Endosomas / Autofagia / Transporte de Proteínas / Proteínas Supresoras de Tumor / Dominios y Motivos de Interacción de Proteínas / Beclina-1 / Lisosomas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos / Endosomas / Autofagia / Transporte de Proteínas / Proteínas Supresoras de Tumor / Dominios y Motivos de Interacción de Proteínas / Beclina-1 / Lisosomas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article