Integrated Methods to Manufacture Hydrogel Microparticles Containing Viral-Metal Nanocomplexes with High Catalytic Activity.

ABSTRACT

Controlled synthesis of small and catalytically active noble metal nanoparticles under mild aqueous conditions is an unmet challenge. Genetically modified tobacco mosaic virus (TMV) can serve as a preferential precursor adsorption and growth sites for the controlled synthesis of palladium (Pd) nanoparticles with high catalytic activity. Here we describe detailed methods for the synthesis of Pd-TMV nanocomplexes as well as their integration into polymeric hydrogel microparticle platforms with controlled dimensions via a simple replica molding process. Such Pd-TMV-containing hydrogel particles may be useful in environmental remediation of toxic chemicals such as carcinogenic dichromate ions.