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Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats.
He, Xiang-Hu; Jordan, Chloe J; Vemuri, Kiran; Bi, Guo-Hua; Zhan, Jia; Gardner, Eliot L; Makriyannis, Alexandros; Wang, Yan-Lin; Xi, Zheng-Xiong.
Afiliación
  • He XH; Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
  • Jordan CJ; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
  • Vemuri K; Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
  • Bi GH; Center for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, 02115, USA.
  • Zhan J; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, USA.
  • Gardner EL; Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
  • Makriyannis A; Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
  • Wang YL; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
  • Xi ZX; Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, 21224, USA.
Acta Pharmacol Sin ; 40(3): 365-373, 2019 Mar.
Article en En | MEDLINE | ID: mdl-29967454
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Receptor Cannabinoide CB1 / Depresión / Comportamiento de Búsqueda de Drogas / Antagonistas de Receptores de Cannabinoides / Dependencia de Heroína Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirazoles / Receptor Cannabinoide CB1 / Depresión / Comportamiento de Búsqueda de Drogas / Antagonistas de Receptores de Cannabinoides / Dependencia de Heroína Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos