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Epigenetics of gastrointestinal diseases: notes from a workshop.
Marks, David L; Olson, Rachel L; Urrutia, Raul; Billadeau, Daniel D; Roy, Nilotpal; Calin, George A; Fabbri, Muller; Koutsioumpa, Marina; Iliopoulos, Dimitrios; Ordog, Tamas; Huebert, Robert; Sarmento, Olga; Bamidele, Adebowale O; Faubion, William; Lomberk, Gwen L; Siveke, Jens; Ahuja, Nita; Iovanna, Juan; Hlady, Ryan A; Robertson, Keith; Kisiel, John; Pin, Christopher L; Fernandez-Zapico, Martin E.
Afiliación
  • Marks DL; a Schulze Center for Novel Therapeutics, Division of Oncology Research , Mayo Clinic , Rochester , MN , USA.
  • Olson RL; a Schulze Center for Novel Therapeutics, Division of Oncology Research , Mayo Clinic , Rochester , MN , USA.
  • Urrutia R; b Division of Research, Department of Surgery , Medical College of Wisconsin , Milwaukee , WI , USA.
  • Billadeau DD; a Schulze Center for Novel Therapeutics, Division of Oncology Research , Mayo Clinic , Rochester , MN , USA.
  • Roy N; c Diabetes Center , University of California at San Francisco , San Francisco , CA , USA.
  • Calin GA; d Department of Experimental Therapeutics, Division of Cancer Medicine , MD Anderson Cancer Center , Houston , TX , USA.
  • Fabbri M; e Children's Center for Cancer and Blood Diseases, Keck School of Medicine of USC , University of Southern California , Los Angeles , CA , USA.
  • Koutsioumpa M; f Laboratory and the Center for Systems Biomedicine , University of California at Los Angeles , Los Angeles , CA , USA.
  • Iliopoulos D; f Laboratory and the Center for Systems Biomedicine , University of California at Los Angeles , Los Angeles , CA , USA.
  • Ordog T; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Huebert R; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Sarmento O; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Bamidele AO; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Faubion W; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Lomberk GL; b Division of Research, Department of Surgery , Medical College of Wisconsin , Milwaukee , WI , USA.
  • Siveke J; h Division of Solid Tumor Translational Oncology, West German Cancer Center , University Hospital Essen , Essen , Germany.
  • Ahuja N; i Department of Surgery , Yale School of Medicine , New Haven , CT , USA.
  • Iovanna J; j Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258 , Institut Paoli-Calmettes , Aix Marseille , France.
  • Hlady RA; k Department of Molecular Pharmacology and Experimental Therapeutics , Mayo Clinic , Rochester , MN , USA.
  • Robertson K; k Department of Molecular Pharmacology and Experimental Therapeutics , Mayo Clinic , Rochester , MN , USA.
  • Kisiel J; g Division of Gastroenterology, Department of Medicine , Mayo Clinic , Rochester , MN , USA.
  • Pin CL; l Division of Genetics & Development, Children's Health Research Institute, Departments of Pediatrics, Physiology and Pharmacology, and Oncology , The University of Western Ontario , London , ON , Canada.
  • Fernandez-Zapico ME; a Schulze Center for Novel Therapeutics, Division of Oncology Research , Mayo Clinic , Rochester , MN , USA.
Epigenetics ; 13(4): 449-457, 2018.
Article en En | MEDLINE | ID: mdl-30056798
ABSTRACT
International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled 'Basic and Translational Facets of the Epigenetics of GI Diseases'. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Epigénesis Genética / Enfermedades Gastrointestinales Tipo de estudio: Screening_studies Límite: Humans Idioma: En Revista: Epigenetics Asunto de la revista: GENETICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Epigénesis Genética / Enfermedades Gastrointestinales Tipo de estudio: Screening_studies Límite: Humans Idioma: En Revista: Epigenetics Asunto de la revista: GENETICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos