Solid-phase extraction of drugs with cuttlefish bone powder as a sorbent.
J Sep Sci
; 41(18): 3547-3552, 2018 Sep.
Article
en En
| MEDLINE
| ID: mdl-30074301
ABSTRACT
We investigated cuttlefish bone powder for the solid-phase extraction of naproxen, ibuprofen, and carbamazepine. The basic principles controlling the extraction are presented to aid in the choice of the nature and quantity of the extracting phase according to the sample matrix and the solute properties, based on the mechanisms of phase retention. Their retention mechanism is based on hydrogen bonding and electrostatic interactions. The results show a significant recovery rate for the three drugs, selectivity, and low cost. The method has successfully reduced the amount of tested pharmaceuticals with recoveries >87% at pH 4.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Polvos
/
Huesos
/
Carbamazepina
/
Ibuprofeno
/
Naproxeno
/
Extracción en Fase Sólida
Límite:
Animals
Idioma:
En
Revista:
J Sep Sci
Año:
2018
Tipo del documento:
Article
País de afiliación:
Túnez