Adaptive mutation F772S-enhanced p7-NS4A cooperation facilitates the assembly and release of hepatitis C virus and is associated with lipid droplet enlargement.

Duan, Xiaobing; Anwar, Muhammad Ikram; Xu, Zhanxue; Ma, Ling; Yuan, Guosheng; Chen, Yiyi; Liu, Xi; Xia, Jinyu; Zhou, Yuanping; Li, Yi-Ping

Duan, Xiaobing; Anwar, Muhammad Ikram; Xu, Zhanxue; Ma, Ling; Yuan, Guosheng; Chen, Yiyi; Liu, Xi; Xia, Jinyu; Zhou, Yuanping; Li, Yi-Ping.

Afiliación

Duan X; Institute of Human Virology and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 501180, China.
Anwar MI; Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-Sen University, Guangzhou, 501180, China.
Xu Z; Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Sun Yat-Sen University, Guangzhou, 510080, China.
Ma L; Institute of Human Virology and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 501180, China.
Yuan G; Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-Sen University, Guangzhou, 501180, China.
Chen Y; Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Sun Yat-Sen University, Guangzhou, 510080, China.
Liu X; Institute of Human Virology and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 501180, China.
Xia J; Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-Sen University, Guangzhou, 501180, China.
Zhou Y; Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology, Sun Yat-Sen University, Guangzhou, 510080, China.
Li YP; Institute of Human Virology and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 501180, China.

Emerg Microbes Infect ; 7(1): 143, 2018 Aug 08.

Article en En | MEDLINE | ID: mdl-30087320

Asunto(s)

Proteínas Portadoras/metabolismo; Hepacivirus/fisiología; Hepatitis C/virología; Gotas Lipídicas/virología; Proteínas no Estructurales Virales/metabolismo; Proteínas Virales/genética; Ensamble de Virus; Liberación del Virus; Secuencia de Aminoácidos; Proteínas Portadoras/química; Proteínas Portadoras/genética; Línea Celular; Hepacivirus/química; Hepacivirus/genética; Hepatitis C/metabolismo; Humanos; Péptidos y Proteínas de Señalización Intracelular; Datos de Secuencia Molecular; Mutación Missense; Alineación de Secuencia; Proteínas no Estructurales Virales/química; Proteínas no Estructurales Virales/genética; Proteínas Virales/metabolismo; Replicación Viral

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Virales / Proteínas Portadoras / Hepatitis C / Proteínas no Estructurales Virales / Hepacivirus / Ensamble de Virus / Liberación del Virus / Gotas Lipídicas Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Emerg Microbes Infect Año: 2018 Tipo del documento: Article País de afiliación: China

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