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Safety and immunogenicity of a plant-produced Pfs25 virus-like particle as a transmission blocking vaccine against malaria: A Phase 1 dose-escalation study in healthy adults.
Chichester, Jessica A; Green, Brian J; Jones, R Mark; Shoji, Yoko; Miura, Kazutoyo; Long, Carole A; Lee, Cynthia K; Ockenhouse, Christian F; Morin, Merribeth J; Streatfield, Stephen J; Yusibov, Vidadi.
Afiliación
  • Chichester JA; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA.
  • Green BJ; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA.
  • Jones RM; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA.
  • Shoji Y; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA.
  • Miura K; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
  • Long CA; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
  • Lee CK; PATH's Malaria Vaccine Initiative, Washington, DC 20001, USA.
  • Ockenhouse CF; PATH's Malaria Vaccine Initiative, Washington, DC 20001, USA.
  • Morin MJ; PATH's Malaria Vaccine Initiative, Washington, DC 20001, USA.
  • Streatfield SJ; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA.
  • Yusibov V; Fraunhofer USA Inc. Center for Molecular Biotechnology, Newark, DE 19711, USA. Electronic address: Vidadi.Yusibov@fhcmb.org.
Vaccine ; 36(39): 5865-5871, 2018 09 18.
Article en En | MEDLINE | ID: mdl-30126674
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Proteínas Protozoarias / Vacunas contra la Malaria / Vacunas de Partículas Similares a Virus / Inmunogenicidad Vacunal Tipo de estudio: Guideline Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Vaccine Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Proteínas Protozoarias / Vacunas contra la Malaria / Vacunas de Partículas Similares a Virus / Inmunogenicidad Vacunal Tipo de estudio: Guideline Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Vaccine Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos