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SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads.
Kinneer, Krista; Meekin, John; Tiberghien, Arnaud C; Tai, Yu-Tzu; Phipps, Sandrina; Kiefer, Christine Mione; Rebelatto, Marlon C; Dimasi, Nazzareno; Moriarty, Alyssa; Papadopoulos, Kyriakos P; Sridhar, Sriram; Gregson, Stephen J; Wick, Michael J; Masterson, Luke; Anderson, Kenneth C; Herbst, Ronald; Howard, Philip W; Tice, David A.
Afiliación
  • Kinneer K; Oncology Research, MedImmune, Gaithersburg, Maryland. kinneerk@medimmune.com.
  • Meekin J; Oncology Research, MedImmune, Gaithersburg, Maryland.
  • Tiberghien AC; Spirogen, QMB Innovation Centre, London, United Kingdom.
  • Tai YT; The Jerome Lipper Multiple Myeloma Center and LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Phipps S; Antibody Discovery and Protein Engineering, MedImmune, Gaithersburg, Maryland.
  • Kiefer CM; Antibody Discovery and Protein Engineering, MedImmune, Gaithersburg, Maryland.
  • Rebelatto MC; Translational Medicine, MedImmune, Gaithersburg, Maryland.
  • Dimasi N; Antibody Discovery and Protein Engineering, MedImmune, Gaithersburg, Maryland.
  • Moriarty A; South Texas Accelerated Research Therapeutics, San Antonio, Texas.
  • Papadopoulos KP; South Texas Accelerated Research Therapeutics, San Antonio, Texas.
  • Sridhar S; Translational Medicine, MedImmune, Gaithersburg, Maryland.
  • Gregson SJ; Spirogen, QMB Innovation Centre, London, United Kingdom.
  • Wick MJ; South Texas Accelerated Research Therapeutics, San Antonio, Texas.
  • Masterson L; Spirogen, QMB Innovation Centre, London, United Kingdom.
  • Anderson KC; The Jerome Lipper Multiple Myeloma Center and LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Herbst R; Oncology Research, MedImmune, Gaithersburg, Maryland.
  • Howard PW; Spirogen, QMB Innovation Centre, London, United Kingdom.
  • Tice DA; Oncology Research, MedImmune, Gaithersburg, Maryland.
Clin Cancer Res ; 24(24): 6570-6582, 2018 12 15.
Article en En | MEDLINE | ID: mdl-30131388
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Benzodiazepinas / Biomarcadores / Inmunoconjugados / Antineoplásicos Inmunológicos / Maitansina Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirroles / Benzodiazepinas / Biomarcadores / Inmunoconjugados / Antineoplásicos Inmunológicos / Maitansina Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article