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Large field of view correction by using conjugate adaptive optics with multiple guide stars.
Zhao, Qi; Shi, Xin; Zhu, Xinpei; Zheng, Yao; Wu, Chenxue; Tang, Hengjie; Hu, Lejia; Xue, Ying; Gong, Wei; Si, Ke.
Afiliación
  • Zhao Q; Center for Neuroscience, Department of Neurobiology, the Second Affiliated Hospital, Zhejiang, University School of Medicine, Hangzhou, Zhejiang, China.
  • Shi X; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Zhu X; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Zheng Y; Center for Neuroscience, Department of Neurobiology, the Second Affiliated Hospital, Zhejiang, University School of Medicine, Hangzhou, Zhejiang, China.
  • Wu C; Center for Neuroscience, Department of Neurobiology, the Second Affiliated Hospital, Zhejiang, University School of Medicine, Hangzhou, Zhejiang, China.
  • Tang H; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Hu L; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Xue Y; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Gong W; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
  • Si K; State Key Laboratory of Modern Optical Instrumentation, Key Laboratory of Medical Neurobiology of Zhejiang Province, College of Optical Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
J Biophotonics ; 12(2): e201800225, 2019 02.
Article en En | MEDLINE | ID: mdl-30141268
ABSTRACT
Adaptive optics has been widely used in the optical microscopy to recover high-resolution images deep into the sample. However, the corrected field of view (FOV) with a single correction is generally limited, which seriously restricts the imaging speed. In this article, we demonstrate a high-speed wavefront correction method by using the conjugate adaptive optical correction with multiple guide stars (CAOMG) based on the coherent optical adaptive technique. The results show that the CAOMG method can greatly improve the corrected FOV. For 120-µm-thick mouse brain tissue, the corrected FOV can be improved up to ~243 times of the conventional pupil adaptive optics (PAO) without additional time consumption. Therefore, this study shows the potential of high-speed imaging through scattering medium in biological science.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dispositivos Ópticos / Imagen Óptica Límite: Animals Idioma: En Revista: J Biophotonics Asunto de la revista: BIOFISICA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dispositivos Ópticos / Imagen Óptica Límite: Animals Idioma: En Revista: J Biophotonics Asunto de la revista: BIOFISICA Año: 2019 Tipo del documento: Article País de afiliación: China