TET2 deficiency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors.

Qu, Xiaoli; Zhang, Shijie; Wang, Shihui; Wang, Yaomei; Li, Wei; Huang, Yumin; Zhao, Huizhi; Wu, Xiuyun; An, Chao; Guo, Xinhua; Hale, John; Li, Jie; Hillyer, Christopher D; Mohandas, Narla; Liu, Jing; Yazdanbakhsh, Karina; Vinchi, Francesca; Chen, Lixiang; Kang, Qiaozhen; An, Xiuli

Qu, Xiaoli; Zhang, Shijie; Wang, Shihui; Wang, Yaomei; Li, Wei; Huang, Yumin; Zhao, Huizhi; Wu, Xiuyun; An, Chao; Guo, Xinhua; Hale, John; Li, Jie; Hillyer, Christopher D; Mohandas, Narla; Liu, Jing; Yazdanbakhsh, Karina; Vinchi, Francesca; Chen, Lixiang; Kang, Qiaozhen; An, Xiuli.

Afiliación

Qu X; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Zhang S; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
Wang S; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Wang Y; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Li W; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Huang Y; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
Zhao H; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Wu X; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
An C; Department of Immunotherapy, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Guo X; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
Hale J; Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Li J; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Hillyer CD; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Mohandas N; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
Liu J; Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yazdanbakhsh K; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
Vinchi F; Red Cell Physiology, New York Blood Center, New York, NY.
Chen L; Erythrocyte Biology Laboratory, School of Life Sciences, Zhengzhou University, Zhengzhou, China.
Kang Q; Laboratory of Membrane Biology, New York Blood Center, New York, NY.
An X; Red Cell Physiology, New York Blood Center, New York, NY.

Blood ; 132(22): 2406-2417, 2018 11 29.

Article en En | MEDLINE | ID: mdl-30254129

Asunto(s)

Proteínas de Unión al ADN/genética; Células Precursoras Eritroides/patología; Mutación con Pérdida de Función; Síndromes Mielodisplásicos/genética; Proteínas Proto-Oncogénicas/genética; Línea Celular Tumoral; Proliferación Celular; Metilación de ADN; Dioxigenasas; Células Precursoras Eritroides/citología; Células Precursoras Eritroides/metabolismo; Eritropoyesis; Eliminación de Gen; Técnicas de Silenciamiento del Gen; Humanos; Síndromes Mielodisplásicos/patología; Proteínas Proto-Oncogénicas c-kit/genética; Regulación hacia Arriba

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Síndromes Mielodisplásicos / Células Precursoras Eritroides / Proteínas Proto-Oncogénicas / Proteínas de Unión al ADN / Mutación con Pérdida de Función Límite: Humans Idioma: En Revista: Blood Año: 2018 Tipo del documento: Article País de afiliación: China

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