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Bile acids induce visceral hypersensitivity via mucosal mast cell-to-nociceptor signaling that involves the farnesoid X receptor/nerve growth factor/transient receptor potential vanilloid 1 axis.
Li, Wen-Ting; Luo, Qing-Qing; Wang, Bo; Chen, Xin; Yan, Xiu-Juan; Qiu, Hong-Yi; Chen, Sheng-Liang.
Afiliación
  • Li WT; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Luo QQ; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Wang B; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Chen X; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Yan XJ; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Qiu HY; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
  • Chen SL; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.
FASEB J ; 33(2): 2435-2450, 2019 02.
Article en En | MEDLINE | ID: mdl-30260705
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Nociceptores / Ácidos y Sales Biliares / Receptores Citoplasmáticos y Nucleares / Factor de Crecimiento Nervioso / Síndrome del Colon Irritable / Canales Catiónicos TRPV / Hipersensibilidad / Mastocitos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Nociceptores / Ácidos y Sales Biliares / Receptores Citoplasmáticos y Nucleares / Factor de Crecimiento Nervioso / Síndrome del Colon Irritable / Canales Catiónicos TRPV / Hipersensibilidad / Mastocitos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China