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Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-ß (Transforming Growth Factor-ß)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans.
Carnevale, Daniela; Facchinello, Nicola; Iodice, Daniele; Bizzotto, Dario; Perrotta, Marialuisa; De Stefani, Diego; Pallante, Fabio; Carnevale, Lorenzo; Ricciardi, Franco; Cifelli, Giuseppe; Da Ros, Francesco; Casaburo, Manuel; Fardella, Stefania; Bonaldo, Paolo; Innocenzi, Gualtiero; Rizzuto, Rosario; Braghetta, Paola; Lembo, Giuseppe; Bressan, Giorgio M.
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  • Carnevale D; From the Department of Molecular Medicine, Sapienza University of Rome, Italy (D.C., M.P., G.L.).
  • Facchinello N; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Iodice D; Department of Molecular Medicine (N.F., D.B., F.D.R., P. Bonaldo, P. Braghetta, G.M.B.), University of Padova, Italy.
  • Bizzotto D; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Perrotta M; Department of Molecular Medicine (N.F., D.B., F.D.R., P. Bonaldo, P. Braghetta, G.M.B.), University of Padova, Italy.
  • De Stefani D; From the Department of Molecular Medicine, Sapienza University of Rome, Italy (D.C., M.P., G.L.).
  • Pallante F; Department of Biomedical Sciences (D.D.S., R.R.), University of Padova, Italy.
  • Carnevale L; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Ricciardi F; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Cifelli G; Department of Neurosurgery (F.R., G.I.), IRCCS Neuromed, Pozzilli, Italy.
  • Da Ros F; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Casaburo M; Department of Molecular Medicine (N.F., D.B., F.D.R., P. Bonaldo, P. Braghetta, G.M.B.), University of Padova, Italy.
  • Fardella S; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Bonaldo P; Department of Angiocardioneurology and Translational Medicine (D.C., D.I., F.P., L.C., G.C., M.C., S.F., G.L.), IRCCS Neuromed, Pozzilli, Italy.
  • Innocenzi G; Department of Molecular Medicine (N.F., D.B., F.D.R., P. Bonaldo, P. Braghetta, G.M.B.), University of Padova, Italy.
  • Rizzuto R; Department of Neurosurgery (F.R., G.I.), IRCCS Neuromed, Pozzilli, Italy.
  • Braghetta P; Department of Biomedical Sciences (D.D.S., R.R.), University of Padova, Italy.
  • Lembo G; Department of Molecular Medicine (N.F., D.B., F.D.R., P. Bonaldo, P. Braghetta, G.M.B.), University of Padova, Italy.
  • Bressan GM; From the Department of Molecular Medicine, Sapienza University of Rome, Italy (D.C., M.P., G.L.).
Arterioscler Thromb Vasc Biol ; 38(10): 2484-2497, 2018 10.
Article en En | MEDLINE | ID: mdl-30354220
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vasoconstricción / Glicoproteínas de Membrana / Factor de Crecimiento Transformador beta1 / Receptores ErbB / Hipertensión / Arterias Mesentéricas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2018 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vasoconstricción / Glicoproteínas de Membrana / Factor de Crecimiento Transformador beta1 / Receptores ErbB / Hipertensión / Arterias Mesentéricas Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2018 Tipo del documento: Article