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Antibacterial Effect of Thiosulfinates on Multiresistant Strains of Bacteria Isolated from Patients with Cystic Fibrosis.
Kulikova, V V; Chernukha, M Yu; Morozova, E A; Revtovich, S V; Rodionov, A N; Koval, V S; Avetisyan, L R; Kuliastova, D G; Shaginyan, I A; Demidkina, T V.
Afiliación
  • Kulikova VV; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
  • Chernukha MY; N.F.Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health of Russian Federation, Gamaleya, Str., 18, Moscow, 123098, Russia.
  • Morozova EA; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
  • Revtovich SV; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
  • Rodionov AN; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
  • Koval VS; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
  • Avetisyan LR; N.F.Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health of Russian Federation, Gamaleya, Str., 18, Moscow, 123098, Russia.
  • Kuliastova DG; N.F.Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health of Russian Federation, Gamaleya, Str., 18, Moscow, 123098, Russia.
  • Shaginyan IA; N.F.Gamaleya National Research Centre of Epidemiology and Microbiology, Ministry of Health of Russian Federation, Gamaleya, Str., 18, Moscow, 123098, Russia.
  • Demidkina TV; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, Vavilova Str., 32, Moscow, 119991, Russia.
Acta Naturae ; 10(3): 77-80, 2018.
Article en En | MEDLINE | ID: mdl-30397530
ABSTRACT
The multiresistance of A. ruhlandii 155B, B. cenocepacia 122, and P. aeruginosa 48B strains isolated from patients with cystic fibrosis was established. The antibacterial effect of allicin, dimethyl thiosulfinate, and dipropyl thiosulfinate on multidrug-resistant strains was shown. Thiosulfinates can have both bacteriostatic and bactericidal effects depending on the microorganism and the concentration. The studied thiosulfinates may be candidates for the development of alternative antibiotic drugs to treat infections caused by multidrug-resistant pathogens.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Acta Naturae Año: 2018 Tipo del documento: Article País de afiliación: Rusia
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Acta Naturae Año: 2018 Tipo del documento: Article País de afiliación: Rusia