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Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.
Heyza, Joshua R; Arora, Sanjeevani; Zhang, Hao; Conner, Kayla L; Lei, Wen; Floyd, Ashley M; Deshmukh, Rahul R; Sarver, Jeffrey; Trabbic, Christopher J; Erhardt, Paul; Chan, Tak-Hang; Dou, Q Ping; Patrick, Steve M.
Afiliación
  • Heyza JR; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. jrheyza@med.wayne.edu.
  • Arora S; Department of Cancer Biology, University of Toledo Health Science Campus, Toledo, OH 43614, USA. sanjeevani.arora@fccc.edu.
  • Zhang H; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. hzhang1@hfhs.org.
  • Conner KL; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. connerk@karmanos.org.
  • Lei W; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. leiwen314@gmail.com.
  • Floyd AM; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. floyda@karmanos.org.
  • Deshmukh RR; Department of Pathology, Wayne State University School of Medicine, Detroit, MI 48201, USA. rdeshmukh@lecom.edu.
  • Sarver J; Department of Pharmacology and Experimental Therapeutics, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA. jeffrey.sarver@utoledo.edu.
  • Trabbic CJ; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA. christrabbic51@gmail.com.
  • Erhardt P; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, OH 43614, USA. paul.erhardt@utoledo.edu.
  • Chan TH; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China. tak-hang.chan@mcgill.ca.
  • Dou QP; Department of Chemistry, McGill University, Montreal, QC H3A 0B8, Canada. tak-hang.chan@mcgill.ca.
  • Patrick SM; Departments of Oncology, Pharmacology, and Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA. doup@karmanos.org.
Nutrients ; 10(11)2018 Nov 03.
Article en En | MEDLINE | ID: mdl-30400270
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Catequina / Cisplatino / Proteínas de Unión al ADN / Reparación del ADN / Endonucleasas / Polifenoles Límite: Animals / Female / Humans Idioma: En Revista: Nutrients Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Catequina / Cisplatino / Proteínas de Unión al ADN / Reparación del ADN / Endonucleasas / Polifenoles Límite: Animals / Female / Humans Idioma: En Revista: Nutrients Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos