Clinical efficacy and pharmaco-economic analysis of xiaozhong zhitong decoction on preventing deep venous thrombosis in major orthopaedic operation.

ABSTRACT

The clinical efficacy and pharmacoeconomics of Xiaozhong Zhitong Decoction on preventing deep venous thrombosis in major orthopaedic operation are observed and analyzed. The 160 patients who are implemented major orthopaedic operation in our hospital are selected as the subjects, which are randomly divided into research group applying Xiaozhong Zhitong decoction and reference group using low molecular heparin with same cases in each group for observing their treatment efficacy and analyzing pharmacoeconomics. Through observing and comparing the rate of deep venous thrombosis in two groups, the results show that study group is significantly lower than reference group with p<0.05. The incidence of adverse reactions in study group is significantly lower than that of reference group with P<0.05; after observing the postoperative quality of life and analyzing cost-effectiveness in two groups, it shows that study group has more significant advantage than reference group with p<0.05. The Xiaozhong Zhitong decoction has a better clinical effect on preventing deep venous thrombosis in major orthopaedic operation with higher safety and reliability and has a better cost effect ratio at the same time.