Genetic profiling-based prognostic prediction of patients with advanced small-cell lung cancer in large scale analysis.

Udagawa, Hibiki; Umemura, Shigeki; Murakami, Isao; Mimaki, Sachiyo; Makinoshima, Hideki; Ishii, Genichiro; Miyoshi, Tomohiro; Kirita, Keisuke; Matsumoto, Shingo; Yoh, Kiyotaka; Niho, Seiji; Tsuchihara, Katsuya; Goto, Koichi

Udagawa, Hibiki; Umemura, Shigeki; Murakami, Isao; Mimaki, Sachiyo; Makinoshima, Hideki; Ishii, Genichiro; Miyoshi, Tomohiro; Kirita, Keisuke; Matsumoto, Shingo; Yoh, Kiyotaka; Niho, Seiji; Tsuchihara, Katsuya; Goto, Koichi.

Afiliación

Udagawa H; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan. Electronic address: hudagawa@east.ncc.go.jp.
Umemura S; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Murakami I; Department of Respiratory Medicine, Higashi-Hiroshima Medical Center, Higashi-Hiroshima, Japan.
Mimaki S; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Makinoshima H; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Ishii G; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Miyoshi T; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Kirita K; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Matsumoto S; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Yoh K; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Niho S; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Tsuchihara K; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Goto K; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

Lung Cancer ; 126: 182-188, 2018 12.

Article en En | MEDLINE | ID: mdl-30527185

Asunto(s)

Genómica/métodos; Neoplasias Pulmonares/genética; Mutación; Carcinoma Pulmonar de Células Pequeñas/genética; Adulto; Anciano; Anciano de 80 o más Años; Femenino; Humanos; Estimación de Kaplan-Meier; Neoplasias Pulmonares/patología; Neoplasias Pulmonares/terapia; Masculino; Persona de Mediana Edad; Proteína Oncogénica v-akt/genética; Proteína Oncogénica v-akt/metabolismo; Fosfatidilinositol 3-Quinasas/genética; Fosfatidilinositol 3-Quinasas/metabolismo; Pronóstico; Proteínas de Unión a Retinoblastoma/genética; Proteínas de Unión a Retinoblastoma/metabolismo; Transducción de Señal/genética; Carcinoma Pulmonar de Células Pequeñas/patología; Carcinoma Pulmonar de Células Pequeñas/terapia; Serina-Treonina Quinasas TOR/genética; Serina-Treonina Quinasas TOR/metabolismo; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo; Ubiquitina-Proteína Ligasas/genética; Ubiquitina-Proteína Ligasas/metabolismo

Palabras clave

Chemotherapy; Genetic alterations; Genome; Small-cell lung cancer; Survival

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genómica / Carcinoma Pulmonar de Células Pequeñas / Neoplasias Pulmonares / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article

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