Designing luminescent ruthenium prodrug for precise cancer therapy and rapid clinical diagnosis.

Zhao, Zhennan; Zhang, Xiang; Li, Chang-E; Chen, Tianfeng

Zhao, Zhennan; Zhang, Xiang; Li, Chang-E; Chen, Tianfeng.

Afiliación

Zhao Z; The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China; Department of Chemistry, Jinan University, Guangzhou, 510632, China.
Zhang X; Department of Chemistry, Jinan University, Guangzhou, 510632, China.
Li CE; Department of Chemistry, Jinan University, Guangzhou, 510632, China.
Chen T; The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China; Department of Chemistry, Jinan University, Guangzhou, 510632, China. Electronic address: tchentf@jnu.edu.cn.

Biomaterials ; 192: 579-589, 2019 02.

Article en En | MEDLINE | ID: mdl-30551086

Asunto(s)

Antineoplásicos/uso terapéutico; Sustancias Luminiscentes/uso terapéutico; Neoplasias/diagnóstico por imagen; Neoplasias/tratamiento farmacológico; Profármacos/uso terapéutico; Rutenio/uso terapéutico; Animales; Antineoplásicos/química; Línea Celular Tumoral; Humanos; Sustancias Luminiscentes/química; Ratones Endogámicos BALB C; Ratones Desnudos; Imagen Óptica; Profármacos/química; Rutenio/química; Nanomedicina Teranóstica; Microambiente Tumoral/efectos de los fármacos

Palabras clave

Cancer theranosis; Rapid clinical diagnosis; Targeted drug delivery; Tumor microenvironment; Two-photon imaging

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Rutenio / Profármacos / Sustancias Luminiscentes / Neoplasias / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Biomaterials Año: 2019 Tipo del documento: Article País de afiliación: China

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