Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca2+-Activated K+ Channel KCa3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells.

Matsui, Miki; Kajikuri, Junko; Kito, Hiroaki; Endo, Kyoko; Hasegawa, Yuki; Murate, Shinya; Ohya, Susumu

Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca²⁺-Activated K⁺ Channel K_Ca3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells.

Matsui, Miki; Kajikuri, Junko; Kito, Hiroaki; Endo, Kyoko; Hasegawa, Yuki; Murate, Shinya; Ohya, Susumu.

Afiliación

Matsui M; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Kajikuri J; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Kito H; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Endo K; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Hasegawa Y; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Murate S; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.).
Ohya S; Department of Pharmacology, Kyoto Pharmaceutical University, Kyoto, Japan (M.M., K.E., Y.H.) and Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan (M.M., J.K., H.K., K.E., S.M., S.O.) sohya@med.nagoya-cu.ac.jp.

Mol Pharmacol ; 95(3): 294-302, 2019 03.

Article en En | MEDLINE | ID: mdl-30622214

Asunto(s)

Interleucina-10/metabolismo; Canales de Potasio de Conductancia Intermedia Activados por el Calcio/metabolismo; Linfoma de Células T/metabolismo; Transducción de Señal/fisiología; Proteína Smad2/metabolismo; Proteína smad3/metabolismo; Transcripción Genética/fisiología; Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina/metabolismo; Línea Celular Tumoral; Núcleo Celular/metabolismo; Proliferación Celular/fisiología; Humanos; Células K562; Fosforilación/fisiología; Células THP-1

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transcripción Genética / Transducción de Señal / Linfoma de Células T / Interleucina-10 / Proteína Smad2 / Proteína smad3 / Canales de Potasio de Conductancia Intermedia Activados por el Calcio Límite: Humans Idioma: En Revista: Mol Pharmacol Año: 2019 Tipo del documento: Article

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