Alginate Hydrogel Modified with a Ligand Interacting with &#945;3ß1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro.

Wen, Han; Xiao, Wenwu; Biswas, Sangita; Cong, Zhao-Qing; Liu, Xin-Min; Lam, Kit S; Liao, Yong-Hong; Deng, Wenbin

Alginate Hydrogel Modified with a Ligand Interacting with α3ß1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro.

Wen, Han; Xiao, Wenwu; Biswas, Sangita; Cong, Zhao-Qing; Liu, Xin-Min; Lam, Kit S; Liao, Yong-Hong; Deng, Wenbin.

Afiliación

Wen H; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences and Peking Union Medical College , 151 Malianwa North Road , Haidian District, Beijing 100193 , China.
Xiao W; Department of Biochemistry and Molecular Medicine, School of Medicine , University of California , 2700 Stockton Blvd , Davis , California 95817 , United States.
Biswas S; Institute for Pediatric Regenerative Medicine , Shriners Hospitals for Children-Northern California , 2425 Stockton Blvd , Sacramento , California 95817 , United States.
Cong ZQ; Department of Biochemistry and Molecular Medicine, School of Medicine , University of California , 2700 Stockton Blvd , Davis , California 95817 , United States.
Liu XM; Department of Biochemistry and Molecular Medicine, School of Medicine , University of California , 2700 Stockton Blvd , Davis , California 95817 , United States.
Lam KS; Institute for Pediatric Regenerative Medicine , Shriners Hospitals for Children-Northern California , 2425 Stockton Blvd , Sacramento , California 95817 , United States.
Liao YH; School of Pharmaceutical Sciences, Shenzhen Campus , Sun Yat-Sen University , 135 Xingang Xi Road , Guangzhou 510275 , China.
Deng W; Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences and Peking Union Medical College , 151 Malianwa North Road , Haidian District, Beijing 100193 , China.

ACS Appl Mater Interfaces ; 11(6): 5821-5833, 2019 Feb 13.

Article en En | MEDLINE | ID: mdl-30645095

Asunto(s)

Alginatos/química; Diferenciación Celular/efectos de los fármacos; Hidrogeles/química; Integrina alfa3beta1/metabolismo; Ligandos; Animales; Técnicas de Cultivo de Célula; Supervivencia Celular/efectos de los fármacos; Proteína Ácida Fibrilar de la Glía/metabolismo; Humanos; Hidrogeles/metabolismo; Hidrogeles/farmacología; Integrina alfa3beta1/química; Ratones; Microscopía Electrónica de Rastreo; Células-Madre Neurales/citología; Células-Madre Neurales/metabolismo; Oligodendroglía/citología; Oligodendroglía/metabolismo; Esferoides Celulares/citología; Esferoides Celulares/efectos de los fármacos; Esferoides Celulares/metabolismo

Palabras clave

3D culture; LXY30; OPC; alginate hydrogel; integrin-ligand; neural progenitor cells; oligodendrocytes; α3ß1

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Diferenciación Celular / Hidrogeles / Integrina alfa3beta1 / Alginatos / Ligandos Límite: Animals / Humans Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2019 Tipo del documento: Article País de afiliación: China

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