Human Pluripotent Stem Cell-Derived Striatal Interneurons: Differentiation and Maturation In Vitro and in the Rat Brain.

Noakes, Zoe; Keefe, Francesca; Tamburini, Claudia; Kelly, Claire M; Cruz Santos, Maria; Dunnett, Stephen B; Errington, Adam C; Li, Meng

Human Pluripotent Stem Cell-Derived Striatal Interneurons: Differentiation and Maturation In Vitro and in the Rat Brain.

Noakes, Zoe; Keefe, Francesca; Tamburini, Claudia; Kelly, Claire M; Cruz Santos, Maria; Dunnett, Stephen B; Errington, Adam C; Li, Meng.

Afiliación

Noakes Z; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK. Electronic address: noakesz@cardiff.ac.uk.
Keefe F; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.
Tamburini C; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK.
Kelly CM; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.
Cruz Santos M; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK.
Dunnett SB; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.
Errington AC; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK.
Li M; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff CF24 4HQ, UK; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK. Electronic address: lim26@cardiff.ac.uk.

Stem Cell Reports ; 12(2): 191-200, 2019 02 12.

Article en En | MEDLINE | ID: mdl-30661995

Asunto(s)

Diferenciación Celular/fisiología; Cuerpo Estriado/citología; Hipocampo/citología; Interneuronas/citología; Células Madre Pluripotentes/citología; Animales; Cuerpo Estriado/metabolismo; Neuronas GABAérgicas/citología; Neuronas GABAérgicas/metabolismo; Hipocampo/metabolismo; Humanos; Interneuronas/metabolismo; Eminencia Media/metabolismo; Eminencia Media/fisiología; Neurogénesis/fisiología; Células Madre Pluripotentes/metabolismo; ARN Mensajero/metabolismo; Ratas

Palabras clave

Huntington's disease; caudal ganglionic eminence; cell replacement therapy; differentiation; human pluripotent stem cells; medial ganglionic eminence; striatal development; striatal interneurons

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Diferenciación Celular / Cuerpo Estriado / Células Madre Pluripotentes / Hipocampo / Interneuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Stem Cell Reports Año: 2019 Tipo del documento: Article

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