Outcomes of salvage surgery for the oropharynx and larynx: a contemporary experience in a UK Cancer Centre.
Eur Arch Otorhinolaryngol
; 276(4): 1153-1159, 2019 Apr.
Article
en En
| MEDLINE
| ID: mdl-30666441
ABSTRACT
INTRODUCTION:
The purpose of this study was to review our recent experience of salvage surgery, comparing larynx and oropharynx recurrence patterns.METHODS:
A single centre, retrospective review of salvage surgery for recurrent head and neck cancer including patients between 2008 and 2016.RESULTS:
61 patients were identified, 36 underwent salvage laryngectomy and 25 received oropharyngeal resections. The median overall survival of oropharyngeal recurrent tumors was 26 months (95% CI 15-118 months) and for laryngeal tumors was 23 months (95% CI 11-38 months), p = 0.1008. There was a significant overall survival benefit in patients with negative resection margin. The median survival in the negative margin group was 38 months (95% CI 25-108 months) compared to the positive margin group, 9 months (95% CI 5-15 months), p < 0.0001.CONCLUSION:
Survival results following surgical salvage in the larynx and oropharynx appear to be similarly poor. Those patients with clear margins appear to have a significantly better prognosis.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Orofaríngeas
/
Neoplasias Laríngeas
/
Terapia Recuperativa
/
Laringectomía
/
Recurrencia Local de Neoplasia
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur Arch Otorhinolaryngol
Asunto de la revista:
OTORRINOLARINGOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Reino Unido