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Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
van Setten, Jessica; Verweij, Niek; Mbarek, Hamdi; Niemeijer, Maartje N; Trompet, Stella; Arking, Dan E; Brody, Jennifer A; Gandin, Ilaria; Grarup, Niels; Hall, Leanne M; Hemerich, Daiane; Lyytikäinen, Leo-Pekka; Mei, Hao; Müller-Nurasyid, Martina; Prins, Bram P; Robino, Antonietta; Smith, Albert V; Warren, Helen R; Asselbergs, Folkert W; Boomsma, Dorret I; Caulfield, Mark J; Eijgelsheim, Mark; Ford, Ian; Hansen, Torben; Harris, Tamara B; Heckbert, Susan R; Hottenga, Jouke-Jan; Iorio, Annamaria; Kors, Jan A; Linneberg, Allan; MacFarlane, Peter W; Meitinger, Thomas; Nelson, Christopher P; Raitakari, Olli T; Silva Aldana, Claudia T; Sinagra, Gianfranco; Sinner, Moritz; Soliman, Elsayed Z; Stoll, Monika; Uitterlinden, Andre; van Duijn, Cornelia M; Waldenberger, Melanie; Alonso, Alvaro; Gasparini, Paolo; Gudnason, Vilmundur; Jamshidi, Yalda; Kääb, Stefan; Kanters, Jørgen K; Lehtimäki, Terho; Munroe, Patricia B.
Afiliación
  • van Setten J; Division Heart & Lungs, Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands. J.vanSetten@umcutrecht.nl.
  • Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Mbarek H; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Niemeijer MN; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Trompet S; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
  • Arking DE; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
  • Brody JA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Gandin I; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Grarup N; Research Unit, AREA Science Park, Trieste, Italy.
  • Hall LM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Hemerich D; Department of Cardiovascular Sciences, University of Leicester, Leicester, England.
  • Lyytikäinen LP; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Groby Road, Leicester, UK.
  • Mei H; Division Heart & Lungs, Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
  • Müller-Nurasyid M; CAPES Foundation, Ministry of Education of Brazil, Brasília, DF, 70040-020, Brazil.
  • Prins BP; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, 33520, Tampere, Finland.
  • Robino A; Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
  • Smith AV; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
  • Warren HR; Department of Medicine I, Ludwig-Maximilians-Universität, Munich, Germany.
  • Asselbergs FW; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
  • Boomsma DI; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Germany.
  • Caulfield MJ; Human Genetics Research Centre, ICCS, St George's University of London, London, UK.
  • Eijgelsheim M; Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.
  • Ford I; Icelandic Heart Association, Kopavogur, Iceland.
  • Hansen T; Faculty of Medicine, University of Iceland, Reykavik, Iceland.
  • Harris TB; William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
  • Heckbert SR; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
  • Hottenga JJ; Division Heart & Lungs, Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands.
  • Iorio A; Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands.
  • Kors JA; Institute of Cardiovascular Science, Faculty of Population Health Sciences, and Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK.
  • Linneberg A; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • MacFarlane PW; William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
  • Meitinger T; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
  • Nelson CP; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.
  • Raitakari OT; Department of Nephrology, University Medical Center Groningen, Groningen, The Netherlands.
  • Silva Aldana CT; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
  • Sinagra G; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sinner M; Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD, USA.
  • Soliman EZ; Cardiovascular Health Research Unit and Department of Epidemiology, University of Washington, Seattle, WA, USA.
  • Stoll M; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Uitterlinden A; Cardiovascular Department, "Ospedali Riuniti and University of Trieste", Trieste, Italy.
  • van Duijn CM; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Waldenberger M; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital-The Capital Region, Copenhagen, Denmark.
  • Alonso A; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Gasparini P; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
  • Gudnason V; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.
  • Jamshidi Y; Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
  • Kääb S; Institute of Human Genetics, Technische Universität München, Munich, Germany.
  • Kanters JK; Department of Cardiovascular Sciences, University of Leicester, Leicester, England.
  • Lehtimäki T; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Groby Road, Leicester, UK.
  • Munroe PB; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland.
Eur J Hum Genet ; 27(6): 952-962, 2019 06.
Article en En | MEDLINE | ID: mdl-30679814
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Electrocardiografía / Sitios Genéticos Tipo de estudio: Clinical_trials / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Eur J Hum Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Electrocardiografía / Sitios Genéticos Tipo de estudio: Clinical_trials / Risk_factors_studies / Systematic_reviews Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Eur J Hum Genet Asunto de la revista: GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos