“The higher the better” seems to be no longer true for HDL-cholesterol.
Vnitr Lek
; 64(12): 1153-1155, 2019.
Article
en En
| MEDLINE
| ID: mdl-30704250
ABSTRACT
It is very well known from the old epidemiological population studies, that HDL-cholesterol (HDL-C) was in a negative association with coronary events risk. New studies have occurred during the last 10 years that the mentioned association has in fact the U-shaped curve, i.e. lower and higher levels of HDL-C then the optimal one are in an exponential increasing risk. The association of high HDL-C levels with cardiovascular risk is not explained clearly. There might be a hypothesis concerning a change of function of large HDL particles riched of cholesterol esters, which become to be cholesterol donors for the arteries. Key words cardiovascular risk - HDL-cholesterol - HDL particles.
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Bases de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Hipercolesterolemia
/
HDL-Colesterol
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Vnitr Lek
Año:
2019
Tipo del documento:
Article