Activation therapy for the treatment of inpatients with depression - protocol for a randomised control trial compared to treatment as usual.
BMC Psychiatry
; 19(1): 52, 2019 02 01.
Article
en En
| MEDLINE
| ID: mdl-30709391
ABSTRACT
BACKGROUND:
Inpatients with depression have a poor long term outcome with high rates of suicide, high levels of morbidity and frequent re-admission. Current treatment often relies on pharmacological intervention and focuses on observation to maintain safety. There is significant neurocognitive deficit which is linked to poor functional outcomes. As a consequence, there is a need for novel psychotherapeutic interventions that seek to address these concerns.METHODS:
We combined cognitive activation and behavioural activation to create activation therapy (AT) for the treatment of inpatient depression and conducted a small open label study which demonstrated acceptability and feasibility. We propose a randomised controlled trial which will compare treatment as usual (TAU) with TAU plus activation therapy for adult inpatients with a major depressive episode. The behavioural activation component involves therapist guided re-engagement with previously or potentially rewarding activities. The cognitive activation aspect utilises computer based exercises which have been shown to improve cognitive function.DISCUSSION:
The proposed randomised controlled trial will examine whether or not the addition of this therapy to TAU will result in a reduced re-hospitalisation rate at 12 weeks post discharge. Subjective change in activation and objectively measured change in activity levels will be rated, and the extent of change to neurocognition will be assessed. TRIAL REGISTRATION Unique trial number U1111-1190-9517. Australian New Zealand Clinical Trials Registry (ANZCTR) number ACTRN12617000024347p .Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Terapia Cognitivo-Conductual
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Trastorno Depresivo Mayor
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Terapia por Ejercicio
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Pacientes Internos
Tipo de estudio:
Clinical_trials
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Guideline
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Qualitative_research
Límite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
BMC Psychiatry
Asunto de la revista:
PSIQUIATRIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Nueva Zelanda