Evaluation of the retinal nerve fiber layer and ganglion cell complex thicknesses in patients with exfoliation syndrome
Turk J Med Sci
; 49(1): 272-278, 2019 Feb 11.
Article
en En
| MEDLINE
| ID: mdl-30761874
ABSTRACT
Background/aim:
This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses using spectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients Materials andmethods:
Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolled in this study. Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmental RNFL thickness and minimum, mean, and segmental GCC thickness.Results:
In the bilateral XFS group, minimum GCC of the right eye (75.80 ± 11.6 µm) was significantly thinner compared with the right eyes of the control group (81.83 ± 6.6 µm) (P < 0.05). Also, superior RNFL was thinner in the right eye (106.90 ± 16.7 µm) compared with left eye (114.15 ± 18.1 µm) in the bilateral XFS group (P < 0.05). No significant differences in the unilateral XFS group were detected in GCC and RNFL analysis.Conclusion:
Minimum GCC value may be the first parameter affected in the conversion of XFS to exfoliative glaucoma followed by RNFL changes.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Células Ganglionares de la Retina
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Síndrome de Exfoliación
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Fibras Nerviosas
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Turk J Med Sci
Año:
2019
Tipo del documento:
Article