Upregulated gga-miR-16-5p Inhibits the Proliferation Cycle and Promotes the Apoptosis of <i>MG</i>-Infected DF-1 Cells by Repressing PIK3R1-Mediated the PI3K/Akt/NF-&#954;B Pathway to Exert Anti-Inflammatory Effect.

Zhang, Kang; Han, Yun; Zhao, Yabo; Sun, Yingfei; Zou, Mengyun; Fu, Yali; Peng, Xiuli

Upregulated gga-miR-16-5p Inhibits the Proliferation Cycle and Promotes the Apoptosis of MG-Infected DF-1 Cells by Repressing PIK3R1-Mediated the PI3K/Akt/NF-κB Pathway to Exert Anti-Inflammatory Effect.

Zhang, Kang; Han, Yun; Zhao, Yabo; Sun, Yingfei; Zou, Mengyun; Fu, Yali; Peng, Xiuli.

Afiliación

Zhang K; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. zhangkang123@webmail.hzau.edu.cn.
Han Y; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. Hany@webmail.hzau.edu.cn.
Zhao Y; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. zyb@webmail.hzau.edu.cn.
Sun Y; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. sunyingfei@webmail.hzau.edu.cn.
Zou M; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. zoumengyun@webmail.hzau.edu.cn.
Fu Y; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. FYL@webmail.hzau.edu.cn.
Peng X; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Technology and College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. xlpengsishun@mail.hzau.edu.cn.

Int J Mol Sci ; 20(5)2019 Feb 27.

Article en En | MEDLINE | ID: mdl-30818821

Asunto(s)

Antiinflamatorios/metabolismo; Apoptosis/genética; Fibroblastos/metabolismo; Fibroblastos/microbiología; MicroARNs/genética; Mycoplasma gallisepticum/fisiología; Transducción de Señal; Regulación hacia Arriba/genética; Animales; Secuencia de Bases; Línea Celular; Proliferación Celular; Embrión de Pollo; Regulación hacia Abajo/genética; Pulmón/microbiología; Pulmón/patología; MicroARNs/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; ARN Mensajero/genética; ARN Mensajero/metabolismo; Enfermedades Respiratorias/genética; Enfermedades Respiratorias/microbiología; Factor de Necrosis Tumoral alfa/biosíntesis; Factor de Necrosis Tumoral alfa/genética

Palabras clave

MG; PI3K/Akt/NF-κB pathway; chicken; gga-miR-16-5p

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Regulación hacia Arriba / Apoptosis / MicroARNs / Mycoplasma gallisepticum / Fibroblastos / Antiinflamatorios Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2019 Tipo del documento: Article País de afiliación: China

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