Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and <i>N</i>-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats.

Jeong, Yoo-Seong; Balla, Anusha; Chun, Kwang-Hoon; Chung, Suk-Jae; Maeng, Han-Joo

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats.

Jeong, Yoo-Seong; Balla, Anusha; Chun, Kwang-Hoon; Chung, Suk-Jae; Maeng, Han-Joo.

Afiliación

Jeong YS; College of Pharmacy, Seoul National University, Seoul 08826, Korea. jus2401@snu.ac.kr.
Balla A; College of Pharmacy, Gachon University, Incheon 21936, Korea. aanushaballa@gmail.com.
Chun KH; College of Pharmacy, Gachon University, Incheon 21936, Korea. khchun@gachon.ac.kr.
Chung SJ; College of Pharmacy, Seoul National University, Seoul 08826, Korea. sukjae@snu.ac.kr.
Maeng HJ; College of Pharmacy, Gachon University, Incheon 21936, Korea. hjmaeng@gachon.ac.kr.

Pharmaceutics ; 11(3)2019 Mar 06.

Article en En | MEDLINE | ID: mdl-30845766

Palabras clave

N-acetylprocainamide; cimetidine; physiologically-based pharmacokinetic modeling for drug-drug interactions; procainamide; rat multidrug and toxin extrusion protein 1; rat organic cation transporter 2

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Pharmaceutics Año: 2019 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Pharmaceutics Año: 2019 Tipo del documento: Article