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Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis.
Hlavac, Michal; Dwucet, Annika; Kast, Richard Eric; Engelke, Jens; Westhoff, Mike-Andrew; Siegelin, Markus D; Debatin, Klaus-Michael; Wirtz, Christian Rainer; Halatsch, Marc-Eric; Karpel-Massler, Georg.
Afiliación
  • Hlavac M; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany.
  • Dwucet A; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany.
  • Kast RE; IIAIG, Study Center, Burlington, VT, USA.
  • Engelke J; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany.
  • Westhoff MA; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
  • Siegelin MD; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
  • Debatin KM; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
  • Wirtz CR; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany.
  • Halatsch ME; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany.
  • Karpel-Massler G; Department of Neurological Surgery, Ulm University Medical Center, Albert-Einstein-Allee 23, D-89081, Ulm, Germany. georg.karpel@uniklinik-ulm.de.
Cell Oncol (Dordr) ; 42(3): 287-301, 2019 Jun.
Article en En | MEDLINE | ID: mdl-30859392

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfonamidas / Apoptosis / Proteína de Unión al GTP rac1 / Ubiquitina Tiolesterasa / Proteínas Reguladoras de la Apoptosis / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Compuestos de Anilina Límite: Humans Idioma: En Revista: Cell Oncol (Dordr) Año: 2019 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sulfonamidas / Apoptosis / Proteína de Unión al GTP rac1 / Ubiquitina Tiolesterasa / Proteínas Reguladoras de la Apoptosis / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Compuestos de Anilina Límite: Humans Idioma: En Revista: Cell Oncol (Dordr) Año: 2019 Tipo del documento: Article País de afiliación: Alemania