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Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.
Ivanova, Hristina; Wagner, Larry E; Tanimura, Akihiko; Vandermarliere, Elien; Luyten, Tomas; Welkenhuyzen, Kirsten; Alzayady, Kamil J; Wang, Liwei; Hamada, Kozo; Mikoshiba, Katsuhiko; De Smedt, Humbert; Martens, Lennart; Yule, David I; Parys, Jan B; Bultynck, Geert.
Afiliación
  • Ivanova H; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
  • Wagner LE; University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
  • Tanimura A; Department of Pharmacology, School of Dentistry, Health Sciences University of Hokkaido, Kita-121757 Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
  • Vandermarliere E; Center for Medical Biotechnology, VIB-UGent, 9000, Ghent, Belgium.
  • Luyten T; Department of Biochemistry, Ghent University, 9000, Ghent, Belgium.
  • Welkenhuyzen K; Bioinformatics Institute Ghent, Ghent University, 9000, Ghent, Belgium.
  • Alzayady KJ; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
  • Wang L; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
  • Hamada K; University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
  • Mikoshiba K; University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 711, Rochester, NY, 14642, USA.
  • De Smedt H; Lab Developmental Neurobiology, RIKEN Brain Science Institute, 2-1 Hirosawa Wako-Shi, 351-0198, Saitama, Japan.
  • Martens L; SIAIS (Shanghai Institute for Advanced Immunochemical Studies), ShanghaiTech University, 393 Middle Huaxia Road, 201210, Shanghai, China.
  • Yule DI; Lab Developmental Neurobiology, RIKEN Brain Science Institute, 2-1 Hirosawa Wako-Shi, 351-0198, Saitama, Japan.
  • Parys JB; SIAIS (Shanghai Institute for Advanced Immunochemical Studies), ShanghaiTech University, 393 Middle Huaxia Road, 201210, Shanghai, China.
  • Bultynck G; Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Cancer Institute (LKI), KU Leuven, Campus Gasthuisberg O/N-1 Bus 802, Herestraat 49, 3000, Leuven, Belgium.
Cell Mol Life Sci ; 76(19): 3843-3859, 2019 Oct.
Article en En | MEDLINE | ID: mdl-30989245
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inositol 1,4,5-Trifosfato / Proteínas Proto-Oncogénicas c-bcl-2 / Señalización del Calcio / Receptores de Inositol 1,4,5-Trifosfato Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inositol 1,4,5-Trifosfato / Proteínas Proto-Oncogénicas c-bcl-2 / Señalización del Calcio / Receptores de Inositol 1,4,5-Trifosfato Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Mol Life Sci Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article País de afiliación: Bélgica