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Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction.
Schmidleithner, Lisa; Thabet, Yasser; Schönfeld, Eva; Köhne, Maren; Sommer, Daniel; Abdullah, Zeinab; Sadlon, Timothy; Osei-Sarpong, Collins; Subbaramaiah, Kotha; Copperi, Francesca; Haendler, Kristian; Varga, Tamas; Schanz, Oliver; Bourry, Svenja; Bassler, Kevin; Krebs, Wolfgang; Peters, Annika E; Baumgart, Ann-Kathrin; Schneeweiss, Maria; Klee, Kathrin; Schmidt, Susanne V; Nüssing, Simone; Sander, Jil; Ohkura, Naganari; Waha, Andreas; Sparwasser, Tim; Wunderlich, F Thomas; Förster, Irmgard; Ulas, Thomas; Weighardt, Heike; Sakaguchi, Shimon; Pfeifer, Alexander; Blüher, Matthias; Dannenberg, Andrew J; Ferreirós, Nerea; Muglia, Louis J; Wickenhauser, Claudia; Barry, Simon C; Schultze, Joachim L; Beyer, Marc.
Afiliación
  • Schmidleithner L; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Thabet Y; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Schönfeld E; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Köhne M; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Sommer D; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Abdullah Z; Institute of Experimental Immunology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
  • Sadlon T; Molecular Immunology, Robinson Research Institute, University of Adelaide, Norwich Centre, 55 King William St, North Adelaide, SA 5006, Australia.
  • Osei-Sarpong C; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Subbaramaiah K; Department of Medicine, Weill Cornell Medical College, 525 E. 68(th) Street, New York, NY 10065, USA.
  • Copperi F; Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany.
  • Haendler K; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Sigmund-Freud-Str. 27, 53127 Bonn, Ge
  • Varga T; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany.
  • Schanz O; LIMES-Institute, Immunology & Environment, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Bourry S; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany.
  • Bassler K; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Krebs W; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Peters AE; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; Institute of Experimental Immunology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
  • Baumgart AK; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; Institute of Experimental Immunology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
  • Schneeweiss M; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Klee K; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Schmidt SV; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Nüssing S; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Sander J; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Ohkura N; Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
  • Waha A; Department of Neuropathology, University Hospital Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.
  • Sparwasser T; Institute for Medical Microbiology and Hygiene (IMMH), Johannes Gutenberg-University Mainz, Obere Zahlbacherstr. 67, 55131 Mainz, Germany.
  • Wunderlich FT; Max Planck Institute for Metabolism Research, Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), Gleueler Str. 50, 50931 Cologne, Germany.
  • Förster I; LIMES-Institute, Immunology & Environment, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Ulas T; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Weighardt H; LIMES-Institute, Immunology & Environment, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany.
  • Sakaguchi S; Laboratory of Experimental Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
  • Pfeifer A; Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany.
  • Blüher M; Department of Medicine, University of Leipzig, Liebigstraße 20, 04103 Leipzig, Germany.
  • Dannenberg AJ; Department of Medicine, Weill Cornell Medical College, 525 E. 68(th) Street, New York, NY 10065, USA.
  • Ferreirós N; Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany.
  • Muglia LJ; Cincinnati Children's Hospital Medical Center, and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Wickenhauser C; Institute for Pathology, Martin-Luther University Halle - Wittenberg, Magdeburger Str. 14, 06112 Halle (Saale), Germany.
  • Barry SC; Molecular Immunology, Robinson Research Institute, University of Adelaide, Norwich Centre, 55 King William St, North Adelaide, SA 5006, Australia.
  • Schultze JL; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, Sigmund-Freud-Str. 27, 53127 Bonn, Ge
  • Beyer M; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Str. 27, 53127 Bonn, Germany; LIMES-Institute, Laboratory for Genomics and Immunoregulation, University of Bonn, Carl-Troll-Str. 31, 53115 Bonn, Germany; PRECISE, Platform for Single Cell Ge
Immunity ; 50(5): 1232-1248.e14, 2019 05 21.
Article en En | MEDLINE | ID: mdl-31027998
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Hidroxiprostaglandina Deshidrogenasas / Linfocitos T Reguladores / Grasa Intraabdominal Límite: Animals / Humans / Male Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dinoprostona / Hidroxiprostaglandina Deshidrogenasas / Linfocitos T Reguladores / Grasa Intraabdominal Límite: Animals / Humans / Male Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania