Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective for In Vitro Eradication of Candida auris Biofilm.
Antimicrob Agents Chemother
; 63(7)2019 07.
Article
en En
| MEDLINE
| ID: mdl-31036689
ABSTRACT
Candida auris poses emerging risks for causing severe central line-associated bloodstream infections. We tested in vitro the ability of antifungal lock solutions to rapidly eradicate C. auris biofilms. Liposomal amphotericin B, amphotericin B deoxycholate, fluconazole, voriconazole, micafungin, caspofungin, and anidulafungin failed to completely eradicate all 10 tested C. auris biofilms. Conversely, nitroglycerin-citrate-ethanol (NiCE) catheter lock solution completely eradicated all replicates for all of C. auris biofilms tested.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Candida
/
Nitroglicerina
/
Ácido Cítrico
/
Catéteres
/
Antifúngicos
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos