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Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7.
Hu, Shanhu; Marineau, Jason J; Rajagopal, Nisha; Hamman, Kristin B; Choi, Yoon Jong; Schmidt, Darby R; Ke, Nan; Johannessen, Liv; Bradley, Michael J; Orlando, David A; Alnemy, Sydney R; Ren, Yixuan; Ciblat, Stephane; Winter, Dana K; Kabro, Anzhelika; Sprott, Kevin T; Hodgson, J Graeme; Fritz, Christian C; Carulli, John P; di Tomaso, Emmanuelle; Olson, Eric R.
Afiliación
  • Hu S; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts. shu@syros.com.
  • Marineau JJ; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Rajagopal N; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Hamman KB; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Choi YJ; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Schmidt DR; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Ke N; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Johannessen L; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Bradley MJ; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Orlando DA; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Alnemy SR; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Ren Y; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Ciblat S; Paraza Pharma, Inc., Quebec City, Canada.
  • Winter DK; Paraza Pharma, Inc., Quebec City, Canada.
  • Kabro A; Paraza Pharma, Inc., Quebec City, Canada.
  • Sprott KT; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Hodgson JG; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Fritz CC; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Carulli JP; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • di Tomaso E; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Olson ER; Syros Pharmaceuticals, Inc., Cambridge, Massachusetts.
Cancer Res ; 79(13): 3479-3491, 2019 07 01.
Article en En | MEDLINE | ID: mdl-31064851
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Apoptosis / Quinasas Ciclina-Dependientes / Inhibidores de Proteínas Quinasas / Proliferación Celular Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Apoptosis / Quinasas Ciclina-Dependientes / Inhibidores de Proteínas Quinasas / Proliferación Celular Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2019 Tipo del documento: Article