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Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.
Makvandi, Mehran; Lee, Hwan; Puentes, Laura N; Reilly, Sean W; Rathi, Komal S; Weng, Chi-Chang; Chan, Ho Sze; Hou, Catherine; Raman, Pichai; Martinez, Daniel; Xu, Kuiying; Carlin, Sean D; Greenberg, Roger A; Pawel, Bruce R; Mach, Robert H; Maris, John M; Pryma, Daniel A.
Afiliación
  • Makvandi M; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. makvandi@pennmedicine.upenn.edu dpryma@pennmedicine.upenn.edu.
  • Lee H; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Puentes LN; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Reilly SW; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Rathi KS; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Weng CC; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Chan HS; Department of Biomedical and Health Informatics and Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Hou C; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Raman P; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Martinez D; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Xu K; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Carlin SD; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Greenberg RA; Department of Biomedical and Health Informatics and Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Pawel BR; Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Mach RH; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Maris JM; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Pryma DA; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Mol Cancer Ther ; 18(7): 1195-1204, 2019 07.
Article en En | MEDLINE | ID: mdl-31072830
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Poli(ADP-Ribosa) Polimerasas / Poli(ADP-Ribosa) Polimerasa-1 / Neuroblastoma Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Poli(ADP-Ribosa) Polimerasas / Poli(ADP-Ribosa) Polimerasa-1 / Neuroblastoma Límite: Animals / Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2019 Tipo del documento: Article