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An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis.
Gertsman, Ilya; Wuu, Joanne; McAlonis-Downes, Melissa; Ghassemian, Majid; Ling, Karen; Rigo, Frank; Bennett, Frank; Benatar, Michael; Miller, Timothy M; Da Cruz, Sandrine.
Afiliación
  • Gertsman I; Biochemical Genetics and Metabolomics Laboratory, Department of Pediatrics, UCSD, La Jolla, California, USA.
  • Wuu J; Clarus Analytical, LLC, San Diego, California, USA.
  • McAlonis-Downes M; Department of Neurology, University of Miami, Miami, Florida, USA.
  • Ghassemian M; Ludwig Institute for Cancer Research and.
  • Ling K; Biomolecular/Proteomics Mass Spectrometry Facility, Department of Chemistry and Biochemistry, UCSD, La Jolla, California, USA.
  • Rigo F; Ionis Pharmaceuticals, Carlsbad, California, USA.
  • Bennett F; Ionis Pharmaceuticals, Carlsbad, California, USA.
  • Benatar M; Ionis Pharmaceuticals, Carlsbad, California, USA.
  • Miller TM; Department of Neurology, University of Miami, Miami, Florida, USA.
  • Da Cruz S; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
JCI Insight ; 4(10)2019 05 16.
Article en En | MEDLINE | ID: mdl-31092730
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos / Biomarcadores / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Péptidos / Biomarcadores / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos