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Human urine contamination with environmental pollutants: simultaneous determination using UPLC-MS/MS.
Beltifa, Asma; Machreki, Monia; Ghorbel, Asma; Belaid, Afifa; Smaoui, Emna; Akrout, Feriele Messadi; Di Bella, Giuseppa; Khdary, Nezar H; Reyns, Tim; Mansour, Hedi Ben; Van Loco, Joris.
Afiliación
  • Beltifa A; Research Unit of Analysis and Process Applied to Environmental-APAE UR17ES32 Higher Institute of Applied Sciences and Technology Mahdia, University of Monastir, Monastir, Tunisia E-mail: hdbenmansour@gmail.com; Faculté des Sciences Mathématiques, Physiques et Naturelles, Université Tunis ElManar, Tu
  • Machreki M; Research Unit of Analysis and Process Applied to Environmental-APAE UR17ES32 Higher Institute of Applied Sciences and Technology Mahdia, University of Monastir, Monastir, Tunisia E-mail: hdbenmansour@gmail.com.
  • Ghorbel A; Hygiene Laboratory/Toxicology Unit, Hedi Chaker Hospital, Sfax, Tunisia.
  • Belaid A; Research Unit of Analysis and Process Applied to Environmental-APAE UR17ES32 Higher Institute of Applied Sciences and Technology Mahdia, University of Monastir, Monastir, Tunisia E-mail: hdbenmansour@gmail.com.
  • Smaoui E; Hygiene Laboratory/Toxicology Unit, Hedi Chaker Hospital, Sfax, Tunisia.
  • Akrout FM; Hygiene Laboratory/Toxicology Unit, Hedi Chaker Hospital, Sfax, Tunisia.
  • Di Bella G; BioMorf Department, University of Messina, Messina, Italy.
  • Khdary NH; Excellence Centers, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
  • Reyns T; Laboratory of Chemical Residues and Contaminants, Direction of Food, Medicines and Consumer Safety, Scientific Institute of Public Health, 1050 Brussels, Belgium.
  • Mansour HB; Research Unit of Analysis and Process Applied to Environmental-APAE UR17ES32 Higher Institute of Applied Sciences and Technology Mahdia, University of Monastir, Monastir, Tunisia E-mail: hdbenmansour@gmail.com.
  • Van Loco J; Laboratory of Chemical Residues and Contaminants, Direction of Food, Medicines and Consumer Safety, Scientific Institute of Public Health, 1050 Brussels, Belgium.
J Water Health ; 17(3): 371-379, 2019 Jun.
Article en En | MEDLINE | ID: mdl-31095513
Paraben derivatives are widely used as an antifungal, antimicrobial preservative in cosmetic products, pharmaceuticals, and food. These molecules are called endocrine disruptors (EDCs). The exposure of the human body to paraben derivatives needs further study and for this purpose 200 urine samples were collected from Tunisian men and women aged between 5 and 90 years to determine three paraben derivatives: methylparaben (MP), ethylparaben (EP) and propylparaben (PP) using ultra performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS). The three major parabens were found in 95 urine samples. The obtained results indicate that MP, EP, and PP were detected in 57%, 46%, and 40% of all samples, respectively. Urinary concentration for the three parabens was in the range of 0.88-84.46 ng/mL, 0.52-29.2 ng/mL, and 0.51-28.17 ng/mL of PP, MP, and EP, respectively. In addition, the concentrations of the paraben derivatives in women were higher than those of men. These findings indicate that the exposure occurs from common products (foods, cosmetics, and pharmaceuticals). The Tunisian authorities should control the composition of packaging of these common products in order to protect humans against EDCs.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Monitoreo del Ambiente / Contaminantes Ambientales Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Water Health Asunto de la revista: SAUDE AMBIENTAL Año: 2019 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Monitoreo del Ambiente / Contaminantes Ambientales Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: J Water Health Asunto de la revista: SAUDE AMBIENTAL Año: 2019 Tipo del documento: Article