Protective effect of gastrodin against methamphetamine-induced autophagy in human dopaminergic neuroblastoma SH-SY5Y cells via the AKT/mTOR signaling pathway.

Yang, Genmeng; Zeng, Xiaofeng; Li, Juan; Leung, Chi-Kwan; Zhang, Dongxian; Hong, Shijun; He, Yongwang; Huang, Jian; Li, Lihua; Li, Zhen

Yang, Genmeng; Zeng, Xiaofeng; Li, Juan; Leung, Chi-Kwan; Zhang, Dongxian; Hong, Shijun; He, Yongwang; Huang, Jian; Li, Lihua; Li, Zhen.

Afiliación

Yang G; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Zeng X; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Li J; School of Basic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Leung CK; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China; CUHK-SDU Joint Laboratory of Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Zhang D; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Hong S; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
He Y; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Huang J; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China.
Li L; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China. Electronic address: lilihua1229@sohu.com.
Li Z; School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, China. Electronic address: lizhenlaura@126.com.

Neurosci Lett ; 707: 134287, 2019 08 10.

Article en En | MEDLINE | ID: mdl-31128157

Asunto(s)

Autofagia/efectos de los fármacos; Alcoholes Bencílicos/farmacología; Estimulantes del Sistema Nervioso Central/farmacología; Neuronas Dopaminérgicas/efectos de los fármacos; Glucósidos/farmacología; Metanfetamina/farmacología; Fármacos Neuroprotectores/farmacología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Serina-Treonina Quinasas TOR/metabolismo; Línea Celular Tumoral; Neuronas Dopaminérgicas/citología; Humanos; Neuroblastoma; Transducción de Señal

Palabras clave

AKT/mTOR; Autophagy; Gastrodin; METH; Methamphetamine; SH-SY5Y cells

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Autofagia / Alcoholes Bencílicos / Fármacos Neuroprotectores / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR / Neuronas Dopaminérgicas / Glucósidos / Estimulantes del Sistema Nervioso Central / Metanfetamina Límite: Humans Idioma: En Revista: Neurosci Lett Año: 2019 Tipo del documento: Article País de afiliación: China

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