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Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells.
Lessard, Christian B; Rodriguez, Edgardo; Ladd, Thomas B; Minter, Lisa M; Osborne, Barbara A; Miele, Lucio; Golde, Todd E; Ran, Yong.
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  • Lessard CB; Department of Neuroscience and Neurology, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, Florida 32610.
  • Rodriguez E; Department of Pharmacology and Therapeutics, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610.
  • Ladd TB; Department of Neuroscience and Neurology, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, Florida 32610.
  • Minter LM; Department of Veterinary and Animal Sciences, Center for Bioactive Delivery, Institute for Applied Life Sciences, and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts 01003.
  • Osborne BA; Department of Veterinary and Animal Sciences, Center for Bioactive Delivery, Institute for Applied Life Sciences, and Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, Massachusetts 01003.
  • Miele L; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112.
  • Golde TE; Department of Neuroscience and Neurology, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, Florida 32610 tgolde@ufl.edu.
  • Ran Y; Department of Neuroscience and Neurology, Center for Translational Research in Neurodegenerative Disease, and McKnight Brain Institute, College of Medicine, University of Florida, Gainesville, Florida 32610 yran@ufl.edu.
J Biol Chem ; 294(29): 11276-11285, 2019 07 19.
Article en En | MEDLINE | ID: mdl-31167792
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Presenilina-1 / Presenilina-2 Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Presenilina-1 / Presenilina-2 Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2019 Tipo del documento: Article