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Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis.
Zhou, Changyang; Sun, Yidi; Yan, Rui; Liu, Yajing; Zuo, Erwei; Gu, Chan; Han, Linxiao; Wei, Yu; Hu, Xinde; Zeng, Rong; Li, Yixue; Zhou, Haibo; Guo, Fan; Yang, Hui.
Afiliación
  • Zhou C; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Ch
  • Sun Y; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
  • Yan R; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
  • Liu Y; CAS Key Laboratory of Systems Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Zuo E; Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Gu C; Center for Translational Medicine, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Obstetrics and Gynecology, West China Second University Hospital, College of Life Sciences, Sichuan University, Chengdu, China.
  • Han L; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.
  • Wei Y; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.
  • Hu X; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Ch
  • Zeng R; Center for Animal Genomics, Agricultural Genome Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
  • Li Y; Center for Translational Medicine, Ministry of Education Key Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Obstetrics and Gynecology, West China Second University Hospital, College of Life Sciences, Sichuan University, Chengdu, China.
  • Zhou H; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Ch
  • Guo F; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Ch
  • Yang H; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Ch
Nature ; 571(7764): 275-278, 2019 07.
Article en En | MEDLINE | ID: mdl-31181567
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN / ARN / Ingeniería de Proteínas / Mutagénesis / Edición Génica / Mutación / Nucleósido Desaminasas Límite: Humans Idioma: En Revista: Nature Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN / ARN / Ingeniería de Proteínas / Mutagénesis / Edición Génica / Mutación / Nucleósido Desaminasas Límite: Humans Idioma: En Revista: Nature Año: 2019 Tipo del documento: Article