Water-soluble metal nanoclusters: recent advances in molecular-level exploration and biomedical applications.
Dalton Trans
; 48(28): 10385-10392, 2019 Jul 16.
Article
en En
| MEDLINE
| ID: mdl-31211305
Water-soluble metal nanoclusters (MNCs) have received extraordinary attention in both fundamental and applied fields due to their ultrasmall size, unique molecular-like properties, rich surface chemistry, benign biocompatibility, and good stability. Currently, the state-of-the-art research on water-soluble MNCs has been upgraded from the nanoscale to the molecular level especially in the following aspects: (1) synthesis of highly luminescent MNCs featuring aggregation-induced emission (AIE), (2) Engineering the ligand shell of MNCs for controllable surface chemistry and (3) Tracking the reductive growth process of MNCs. Such molecular-level research progress of water-soluble MNCs in turn facilitated their development in biomedical applications. In this Frontier Article, we start our discussion by briefly summarizing the recent molecular-level research progress of water-soluble MNCs in the above-mentioned three aspects, followed by our perspectives on these fundamental aspects. Afterwards, the latest advance in biomedical applications of water-soluble MNCs is discussed. We hope that this Frontier Article could stimulate more studies on the molecular- or atomic-level understanding and biomedical applications of water-soluble MNCs.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Materiales Biocompatibles
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Investigación Biomédica
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Nanopartículas del Metal
Límite:
Animals
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Humans
Idioma:
En
Revista:
Dalton Trans
Asunto de la revista:
QUIMICA
Año:
2019
Tipo del documento:
Article